Basic Information
VIS ID
TVIS44031712
Fusion event
HTLV-1-ALKAL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
NCBI36/hg18
Start
270370/280370 (Hg38)
End
270370/280370 (Hg38)
Orient
+
Location type
Intronic
Target gene
ALKAL2
miRNAs that regulate target gene
hsa-mir-16-5p
Nearest miRNA
hsa-mir-10b/Downstream/5694292;
Nearest TSS
ENST00000437798/Upstream/5797; ENST00000619113/Downstream/6549;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/15132, chr2-CpG: 263/Downstream/6983
Upstream sequence
TGCATCTGTATTTCTCTGTGATCCAAAAAGTGTAGTCTATTGTATTTTTAAAAATACCTTCTTTCTGCAGTTGTTACATGGCTGCAATGCTAAAGCAATG
Downstream sequence
AAAATCATCACAGATACATGTGGATGCTTTATTACAGCTTGAAGAGTGCTTAGTCTTACATGTGCTATCAGAATCCTCAGTAGTCTAGGCCACAGGGATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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