Basic Information
VIS ID
TVIS44031716
Fusion event
HTLV-1-EVC2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
p16.2
Reference genome
NCBI36/hg18
Start
5742869/5690241 (Hg38)
End
5742869/5690241 (Hg38)
Orient
-
Location type
Intronic
Target gene
EVC2
miRNAs that regulate target gene
hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-3942-3p ; hsa-mir-6873-3p ; hsa-mir-5100 ; hsa-mir-4722-5p ; hsa-mir-6721-5p ; hsa-mir-942-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-5088-3p ; hsa-mir-6729-3p ; hsa-mir-4768-3p ; hsa-mir-1245b-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p
Nearest miRNA
hsa-mir-4800/Upstream/3440085; hsa-mir-12113/Downstream/233034;
Nearest TSS
ENST00000502981/Upstream/252324; ENST00000514919/Downstream/18326;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/121617, chr4-CpG: 56/Downstream/18017
Upstream sequence
cacttataactgcatgcatatggcagaaaaagtcactagaaggatatacaagaaactactaacactgattgcatccaggaagGCAAACAATGTAGTTGAG
Downstream sequence
GGCCTGTGATAAAATGAGGGTGGCAcaggaaaggcttaactcagcaggcctgggctgtccaaaccctccacattcaggagaaaggactggcccttgagca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate