Basic Information
VIS ID
TVIS44031726
Fusion event
HTLV-1-RCAN2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
46487775/46412079 (Hg38)
End
46487775/46412079 (Hg38)
Orient
-
Location type
Intronic
Target gene
RCAN2
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-4482-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-138-2-3p ; hsa-mir-1284 ; hsa-mir-205-3p ; hsa-mir-3168 ; hsa-mir-4666a-3p ; hsa-mir-5580-3p ; hsa-mir-338-5p ; hsa-mir-148a-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-340-5p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6777-3p ; hsa-mir-513b-3p
Nearest miRNA
hsa-mir-10398/Upstream/1214309; hsa-mir-10524/Downstream/5732270;
Nearest TSS
ENST00000381078/Upstream/86407; ENST00000415787/Downstream/79283;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/281863, chr6-CpG: 58/Downstream/79062
Upstream sequence
aggtctctctggctgctgtgaagagcctggattgtaggcagtccaacagtggaagcaggaataccagctagggagattactacggaaaagagacaatggt
Downstream sequence
gacttgatctaaaatattagtggtggagacagggtgaagaaatttgatccaggatttatgaggtagatctcctgggacttgtatatggattatatattaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate