Basic Information
VIS ID
TVIS44031727
Fusion event
HTLV-1-MMP16 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
89170236/88088892 (Hg38)
End
89170236/88088892 (Hg38)
Orient
-
Location type
Intronic
Target gene
MMP16
miRNAs that regulate target gene
hsa-mir-146b-5p ; hsa-mir-31-5p ; hsa-mir-328-3p ; hsa-mir-155-5p ; hsa-mir-218-5p ; hsa-mir-4712-3p ; hsa-mir-548at-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-325 ; hsa-mir-628-3p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-let-7c-3p ; hsa-mir-7158-5p ; hsa-mir-3171 ; hsa-mir-29b-1-5p ; hsa-mir-767-3p ; hsa-mir-4502 ; hsa-mir-4693-5p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-6796-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-145-3p
Nearest miRNA
hsa-mir-12123/Upstream/7847419; hsa-mir-10400/Downstream/3116593;
Nearest TSS
ENST00000518652/Upstream/114727; ENST00000520849/Downstream/237944;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/214675, chr8-CpG: 25/Downstream/239004
Upstream sequence
TTCTAAGGCAGTCTTGAGGGAAGTCAGATGATCACAATCATTAACGAATGGAAAACACTGTGCTACTGGGTCATTTTTATGGGTTTTACCCATGAATTAC
Downstream sequence
TGTTGAATACAAAAGCAATTGGAGAAAGTTCTAAAAAATAAAAATAAGTCAGTAAGTTTCCTAATCATTCAGCAAAATAATGAAGCCTTGAACAATTATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate