Basic Information
VIS ID
TVIS44031750
Fusion event
HTLV-1-WDFY2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
NCBI36/hg18
Start
51128020/51655883 (Hg38)
End
51128020/51655883 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDFY2
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-19b-3p ; hsa-mir-2355-3p ; hsa-mir-3942-3p ; hsa-mir-676-3p ; hsa-mir-6749-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-5100 ; hsa-mir-124-5p ; hsa-mir-6852-3p ; hsa-mir-4437 ; hsa-mir-3909 ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-545-3p ; hsa-mir-10b-3p ; hsa-mir-4255 ; hsa-mir-24-3p
Nearest miRNA
hsa-mir-15a/Upstream/103216; hsa-mir-1267/Downstream/1154167;
Nearest TSS
ENST00000623511/Upstream/71375; ENST00000460145/Downstream/83265;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/70784, chr13-CpG: 96/Downstream/147802
Upstream sequence
gttttgcacttttctttgttgagaagtttttgattattgattcaatctctacttgtaataggtttgttgagattatccatttcttcttgagtcagtattg
Downstream sequence
gtagattgtatgtttctaggaatttgtttatttaatctagattatctaattggctggcatataaattttctcctataatcctttaaatttctgtttagct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate