Basic Information
VIS ID
TVIS44031759
Fusion event
HTLV-1-BOC integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
114445448/113243911 (Hg38)
End
114445448/113243911 (Hg38)
Orient
-
Location type
Intronic
Target gene
BOC
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-21-5p ; hsa-mir-6738-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-148a-5p
Nearest miRNA
hsa-let-7g/Upstream/506730; hsa-mir-12124/Downstream/188207;
Nearest TSS
ENST00000440867/Upstream/27560; ENST00000477178/Downstream/17787;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/31252, chr3-CpG: 32/Downstream/197541
Nearest cancer related gene
BOC(OG, No orient, 0)
Upstream sequence
TGCCTCTGCTCTCATTTGCCACTTCACATTGGTGACTGAACTGATCAGTGAAAGTATTAAAGAATGCTAAAGTTGTTACAGGAGAATAATCACAAAATTT
Downstream sequence
CAGTGGTTTTGTGCAACAAACCTCTTCTCATGTCACATCTTGAGCTAATTGCTTCGATCTTATAGCTGTGCCTTCTGAACCATGTGACATATGGTCACCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate