Basic Information
VIS ID
TVIS44031761
Fusion event
HTLV-1-AKIRIN2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
NCBI36/hg18
Start
88453145/87686708 (Hg38)
End
88453145/87686708 (Hg38)
Orient
+
Location type
Intronic
Target gene
AKIRIN2
miRNAs that regulate target gene
hsa-mir-4671-3p ; hsa-mir-6073 ; hsa-mir-423-3p ; hsa-mir-216b-3p ; hsa-mir-4637 ; hsa-mir-4668-3p ; hsa-mir-142-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-130b-3p ; hsa-mir-4295 ; hsa-mir-454-3p
Nearest miRNA
hsa-mir-10398/Upstream/9147399; hsa-mir-1202/Downstream/2626034;
Nearest TSS
ENST00000381078/Upstream/35778; ENST00000237201/Downstream/14817;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/96481, chr6-CpG: 106/Downstream/14716
Nearest cancer related gene
AKIRIN2(OG, No orient, 0)
Upstream sequence
TCGCGAACAGTTTTAAGTTTAGGTGTATGGGGCCCCTCTGTACCATTTTATAGGTCAATACCATTTATTTCTCCATGGAATATCTTTGGAAAACACAAAA
Downstream sequence
TGAAAGTGGACCTAGAAAGACAATTCAAACAATGGAATTGAAAAAGAAATCTTGTggccgggcgcggtagttcatgcctgtaatcccagcactttggaag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate