Basic Information
VIS ID
TVIS44031781
Fusion event
HTLV-1-ELAVL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
23685486/23695488 (Hg38)
End
23685486/23695488 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
ELAVL2
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-mir-200c-3p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-4477a ; hsa-mir-3194-3p ; hsa-mir-3607-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-17-5p ; hsa-mir-106a-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-520d-3p ; hsa-mir-520e ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-4639-5p ; hsa-mir-500a-3p ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-6804-3p ; hsa-mir-539-5p ; hsa-mir-4521 ; hsa-mir-4712-3p ; hsa-mir-541-5p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-6739-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-665 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-4272 ; hsa-mir-548l ; hsa-mir-375 ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-101-2/Upstream/2183303; hsa-let-7a-1/Downstream/5168138;
Nearest TSS
ENST00000422679/Upstream/23089; ENST00000423440/Downstream/40077;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1247792, chr9-CpG: 156/Downstream/125205
Upstream sequence
TCATGCTTTGCTACCACCCACTCAGGACACCAAGCATACGGCCCAGAGACAGATGAGTTTTCAGAATTTTCAAACAGGGTAGAAACCAAATCTGCCCCTG
Downstream sequence
AAGTGAATTACCgtcaggccttttttaacaatggggatatgttctgaaaatgtgtcactaggtgatctcgttgttgtacgatcatagaatgcacttatac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate