Basic Information
VIS ID
TVIS44031789
Fusion event
HTLV-1-GRIN2B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p13.1
Reference genome
NCBI36/hg18
Start
13796193/13751992 (Hg38)
End
13796193/13751992 (Hg38)
Orient
+
Location type
Intronic
Target gene
GRIN2B
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6807-5p ; hsa-mir-4303 ; hsa-mir-6873-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4267 ; hsa-mir-6858-3p ; hsa-mir-1179 ; hsa-mir-4762-3p ; hsa-mir-4766-5p ; hsa-mir-3160-5p ; hsa-mir-500a-5p ; hsa-mir-495-5p ; hsa-mir-6749-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4769-3p ; hsa-mir-4469 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-5196-3p ; hsa-mir-6502-3p ; hsa-mir-126-3p ; hsa-mir-3180-5p ; hsa-mir-6515-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-501-5p ; hsa-mir-670-3p ; hsa-mir-1304-3p ; hsa-mir-3691-3p ; hsa-mir-483-3p ; hsa-mir-3184-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-6849-3p ; hsa-mir-3614-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-5699-5p ; hsa-mir-519d-5p ; hsa-mir-1265 ; hsa-mir-4257
Nearest miRNA
hsa-mir-1244-3/Upstream/836074; hsa-let-7i/Downstream/3921307;
Nearest TSS
ENST00000382841/Upstream/76172; ENST00000538329/Downstream/227991;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/187892, chr12-CpG: 23/Downstream/229700
Upstream sequence
taaggagccccagatggaactggaatagaaggaaaccagagaggtagaagaaaaaccaagacaatctgTGCCAAGCAAGGGGCAATACCTAGGGATGATG
Downstream sequence
GAAAGAGGAACCTCTAGAGAGTTGATGGTGGAAGAATATCAAGATTGGATCACAGATATAACTACTGTGAACCTGGTTTGAGTTTCAACCCTGAATTGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate