Basic Information
VIS ID
TVIS44031804
Fusion event
HTLV-1-ZDHHC14 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
NCBI36/hg18
Start
157769317/157428297 (Hg38)
End
157769317/157428297 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZDHHC14
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-130b-3p ; hsa-mir-587 ; hsa-mir-5581-3p ; hsa-mir-3140-3p ; hsa-mir-6872-3p ; hsa-mir-302f ; hsa-mir-451a ; hsa-mir-6511b-5p ; hsa-mir-676-5p ; hsa-mir-6811-5p
Nearest miRNA
hsa-mir-10398/Upstream/648566; hsa-mir-1913/Downstream/100835;
Nearest TSS
ENST00000381078/Upstream/47164; ENST00000523468/Downstream/114288;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/45952, chr6-CpG: 29/Downstream/164483
Upstream sequence
GGTGGCAGCAACACAGTAGGAAGATAAAGGGCTGCACACACACCACAGAGACCCTGCCCACTCCCACCCTCCGGTGCCCCGACCTTGCCAGCTCCTCTGC
Downstream sequence
CATAGAAATCCTCTCAGGAAAGTGGACTGGATTTGCCAAGCAGGGTAGTGTTTTTCTAAACCAGTGATCTGGGAACTGGTATTCGTCTAAAATTAGCCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate