Basic Information
VIS ID
TVIS44031812
Fusion event
HTLV-1-RNF20 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
103348372/101546269 (Hg38)
End
103348372/101546269 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNF20
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-1296-5p ; hsa-mir-1254 ; hsa-mir-3116 ; hsa-mir-3686 ; hsa-mir-921 ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-4786-3p ; hsa-mir-3182 ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-877-3p ; hsa-mir-3174 ; hsa-mir-4535 ; hsa-mir-4750-5p ; hsa-mir-4776-5p ; hsa-mir-1273e ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-4722-5p ; hsa-mir-6087 ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-302f ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-1303 ; hsa-mir-3674 ; hsa-mir-744-3p ; hsa-mir-6514-3p ; hsa-mir-6894-3p ; hsa-mir-6867-3p ; hsa-mir-6883-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-661 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-4781-3p ; hsa-mir-454-5p ; hsa-mir-483-5p
Nearest miRNA
hsa-let-7a-1/Upstream/3317052; hsa-mir-12126/Downstream/5054659;
Nearest TSS
ENST00000422679/Upstream/12290; ENST00000478072/Downstream/14412;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/12319, chr9-CpG: 115/Downstream/191298
Upstream sequence
ttgtgtcatgttttaaaacctagcacaAAGGGTATATATAGATTAATGTGAACTTGTAATAGTTTAGTAGTTAAAATACTAAATAGTGTTAGCTGGTGTA
Downstream sequence
TAGCTCCTAAATAGAGTATCTGACTTTAGATTATAGTATAATCTATACTGTATTGTATCTGACTCTAGATTGCTCTGGGGTGAGCTTAAAAAAGAGTATG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate