Basic Information
VIS ID
TVIS44031824
Fusion event
HTLV-1-CRTC3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
NCBI36/hg18
Start
88921041/90576805 (Hg38)
End
88921041/90576805 (Hg38)
Orient
-
Location type
Intronic
Target gene
CRTC3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-671-5p ; hsa-mir-92a-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-29b-2-5p ; hsa-mir-6079 ; hsa-mir-6828-5p ; hsa-mir-4772-5p ; hsa-mir-4487 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-29b-1-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-383-5p ; hsa-mir-6768-5p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-10393/Upstream/569964; hsa-mir-1302-10/Downstream/2327594;
Nearest TSS
ENST00000557528/Upstream/37188; ENST00000561290/Downstream/16907;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/46061, chr15-CpG: 72/Downstream/88283
Upstream sequence
aatgttttcaatagagcaaactgtcagtaatttccagtgttccaagaggtcaggagctgaaaatgcccatttggatttagtagcgtgcaaagtctgtggt
Downstream sequence
tatcttgggaaatttcggtggagcagagggatgggggctgaggtctgtgggagttgaggaagtggagttgaggcaactccttcatcacaaagcttggctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate