Basic Information
VIS ID
TVIS44031827
Fusion event
HTLV-1-LRP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
169698141/169133385 (Hg38)
End
169698141/169133385 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRP2
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-mir-146a-5p
Nearest miRNA
hsa-mir-128-1/Upstream/550367; hsa-mir-10b/Downstream/6034248;
Nearest TSS
ENST00000437798/Upstream/32642; ENST00000469980/Downstream/6278;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/242890, chr2-CpG: 119/Downstream/228419
Upstream sequence
GAATGCATAATAAACTACAAGGTAGACAATTCACTCCTTTTCCTATATTTTCACATTCATTACTTGTTTATTCTGAAACTTGGATATGCATTTGTATACA
Downstream sequence
TGGCCTCATTTTATTTTAAGTGAAGATGTCAAATGAAATGTCGTATCTCTTTTATCATGTGATTAAAGTTTTCATATCTGTTTATCAGAGGATCAGGGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate