Basic Information
VIS ID
TVIS44031837
Fusion event
HTLV-1-NSUN3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
NCBI36/hg18
Start
95287752/94086218 (Hg38)
End
95287752/94086218 (Hg38)
Orient
-
Location type
Intronic
Target gene
NSUN3
miRNAs that regulate target gene
hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-526b-5p ; hsa-mir-223-3p ; hsa-mir-6804-5p ; hsa-mir-935 ; hsa-mir-6507-3p ; hsa-mir-4423-3p ; hsa-mir-6758-3p ; hsa-mir-6777-3p ; hsa-mir-455-3p ; hsa-mir-4639-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-324-5p ; hsa-mir-4536-3p ; hsa-mir-6767-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-153-5p
Nearest miRNA
hsa-let-7g/Upstream/6859941; hsa-mir-12124/Downstream/2273746;
Nearest TSS
ENST00000440867/Upstream/9876; ENST00000466089/Downstream/851954;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/22954, chr3-CpG: 41/Downstream/851670
Upstream sequence
tttttaatagagatggggtttcaccatgttggccaggctggtctcaaactcttgacctcaagtgatctgcccacctgggcctccctaagtgctgtgagcc
Downstream sequence
actgtgcctggctgacttattcacttcctcaGCCAAaacactgatgtgttgaactgcccttgtttgatgttctggaggtttcgataccctggcacattct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate