Basic Information
VIS ID
TVIS44031838
Fusion event
HTLV-1-IL11 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
NCBI36/hg18
Start
60568548/55365368 (Hg38)
End
60568548/55365368 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
IL11
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-379-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30c-5p
Nearest miRNA
hsa-let-7e/Upstream/120118; hsa-mir-10394/Downstream/22813;
Nearest TSS
ENST00000633603/Upstream/2108; ENST00000291934/Downstream/3873;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2743, chr19-CpG: 78/Downstream/3841
Upstream sequence
gaacccgggaggtggaggttgcagtgacctcagattgcctcactgcactccagcctaggcaacagagcgagactccatctcaaaaaacaaacaaaaGGCC
Downstream sequence
CTATGCAGTGCGGGGCCCCAGGCAAGGCTCAGACCCTGCCTCCACAGAGCTGTCTGGGTGACCGACCCATCTCCCAGTCGCTGCCCCGCCCACTCGGGAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate