Basic Information
VIS ID
TVIS44031861
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
NCBI36/hg18
Start
89218095/88979824 (Hg38)
End
89218095/88979824 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
KYAT3 ; RBMXL1
miRNAs that regulate target gene
hsa-mir-421 ; hsa-let-7b-5p ; hsa-mir-340-5p ; hsa-mir-124-3p ; hsa-let-7a-5p ; hsa-mir-1260b ; hsa-mir-192-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-6793-5p ; hsa-mir-4480 ; hsa-mir-7847-3p ; hsa-mir-496 ; hsa-mir-1915-5p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-129-5p ; hsa-mir-5004-3p ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-4716-5p ; hsa-mir-7850-5p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-587 ; hsa-mir-5587-5p ; hsa-mir-6826-3p ; hsa-mir-3682-5p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-5002-5p ; hsa-mir-7159-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-3168 ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-148a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548t-5p ; hsa-mir-548az-5p
Nearest miRNA
hsa-mir-101-1/Upstream/2622137; hsa-mir-11399/Downstream/4867008;
Nearest TSS
ENST00000473358/Upstream/87880; ENST00000641099/Downstream/8531;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/88116, chr1-CpG: 52/Downstream/12527
Upstream sequence
aaaagggtatagcccctttggaaaacaaacagtttggcagttactttattaaacataaatctgccatgcaacccaaccattttactggtaggtatttacc
Downstream sequence
caagagaaaggaaaacctatgtctacacagtggcttgtacacaaatgttcctaacagttttattcacagtagccccaaactggaaacaatcccaaggtcc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate