Basic Information
VIS ID
TVIS44031888
Fusion event
HTLV-1-YWHAQ integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
NCBI36/hg18
Start
9674217/9616637 (Hg38)
End
9674217/9616637 (Hg38)
Orient
+
Location type
Intronic
Target gene
YWHAQ
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-214-3p ; hsa-mir-1910-5p ; hsa-mir-193b-3p ; hsa-mir-424-5p ; hsa-mir-423-3p ; hsa-mir-328-3p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-mir-620 ; hsa-mir-578 ; hsa-mir-1270 ; hsa-mir-6505-5p ; hsa-mir-526b-5p ; hsa-mir-4683 ; hsa-mir-4635 ; hsa-mir-3691-3p ; hsa-mir-511-3p ; hsa-mir-576-3p ; hsa-mir-302a-5p ; hsa-mir-545-3p ; hsa-mir-4496 ; hsa-mir-5586-3p ; hsa-mir-651-3p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-7702 ; hsa-mir-5011-3p ; hsa-mir-151a-3p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-20a-3p ; hsa-mir-342-3p ; hsa-mir-4717-3p ; hsa-mir-4719 ; hsa-mir-4762-5p ; hsa-mir-3688-3p ; hsa-mir-890 ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-548n
Nearest miRNA
hsa-mir-7158/Upstream/2966198; hsa-mir-10b/Downstream/575977;
Nearest TSS
ENST00000437798/Upstream/60738; ENST00000478468/Downstream/4064;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/60160, chr2-CpG: 145/Downstream/13423
Nearest cancer related gene
YWHAQ(OG, No orient, 0)
Upstream sequence
atcatctatctgataaaggtctagtatccataatatatttaaaaaaaaaaaagattacaacccaatgataaaaacacaaataacccaattttaaaacaag
Downstream sequence
caaaggatctgaacagacatttctccaaagagcatatactaaaggccaataagtacatgaTACCATTTCATATCCACCAGGAttggtgaggatgtagaga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate