Basic Information
VIS ID
TVIS44031894
Fusion event
HTLV-1-CEP128 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
80436371/80900274 (Hg38)
End
80436371/80900274 (Hg38)
Orient
-
Location type
Intronic
Target gene
CEP128
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-10a-5p ; hsa-mir-6755-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-4762-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-1260a/Upstream/3633984; hsa-mir-1185-1/Downstream/13047952;
Nearest TSS
ENST00000550708/Upstream/63938; ENST00000557096/Downstream/4654;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1038286, chr14-CpG: 29/Downstream/41092
Upstream sequence
AGAAAAAAATTTTCCAAGAAAAACAAATTTTTAAAAGCTGTATATAACATTTATCAACACATTTTCTACAGTACAATTCTACTCCTCCAGAATTCTACCC
Downstream sequence
CTCTAGAAGGGGTCTGCTTCTTCCTTAATCAGAGCAAAAGAAAAAGAAAAAAGAGAGAGCGAGAAAGAAGGAGAAAACCggtctgccaatttttctgtaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate