Basic Information
VIS ID
TVIS44031895
Fusion event
HTLV-1-FAM49A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p24.2
Reference genome
NCBI36/hg18
Start
16627119/16582370 (Hg38)
End
16627119/16582370 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAM49A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-8485 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-2110 ; hsa-mir-25-3p ; hsa-mir-3150a-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4271 ; hsa-mir-450a-2-3p ; hsa-mir-4725-3p ; hsa-mir-621 ; hsa-mir-6763-5p ; hsa-mir-6780b-5p ; hsa-mir-6810-5p ; hsa-mir-6857-5p ; hsa-mir-92a-1-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-3125/Upstream/3844926; hsa-mir-10b/Downstream/2766059;
Nearest TSS
ENST00000437798/Upstream/20888; ENST00000423925/Downstream/83458;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/73816, chr2-CpG: 29/Downstream/956518
Upstream sequence
ATGTCAGCATTAGGCAGAAGAAAAGAATTGGATCTTCCAAAAGAATCCTTTTTTAAAAACAAAAAAAATTTACaactttgttgagatttaattcacgtgc
Downstream sequence
catacgatttgcccatttaaagtgcataattaaacagtttaaaatatattcttagtgttgtgcaaccatcattacaatcagttttagaacattttcatta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate