Basic Information
VIS ID
TVIS44031900
Fusion event
HTLV-1-PIGX integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
NCBI36/hg18
Start
197929835/196718567 (Hg38)
End
197929835/196718567 (Hg38)
Orient
-
Location type
Intronic
Target gene
PIGX
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-122-5p ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4430 ; hsa-mir-4524a-3p ; hsa-mir-4639-3p ; hsa-mir-4797-5p ; hsa-mir-5007-5p ; hsa-mir-504-3p ; hsa-mir-5698 ; hsa-mir-6794-3p ; hsa-mir-6864-3p ; hsa-mir-8055
Nearest miRNA
hsa-let-7g/Upstream/836172; hsa-mir-4797/Downstream/575311;
Nearest TSS
ENST00000440867/Upstream/5845; ENST00000481344/Downstream/21290;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/5704, chr3-CpG: 79/Downstream/21147
Upstream sequence
cagataccttttcttcctctgttttgagaggatcatacaatttttatattttattctcttaatatgatgaagtacattgatgtttccagtagtgaacgta
Downstream sequence
ctccttggtcatgcgatattatcttcttgaaatatatctggatatgttttgctaataacttgcttagtatttttacttgtatgttcatgaaggctactgg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate