Basic Information
VIS ID
TVIS44031914
Fusion event
HTLV-1-C5orf24 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
134204718/134841129 (Hg38)
End
134204718/134841129 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
C5orf24
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-22-3p ; hsa-mir-183-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-32-3p ; hsa-mir-379-3p ; hsa-mir-411-3p ; hsa-mir-651-3p ; hsa-mir-4495 ; hsa-mir-548an ; hsa-mir-380-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-466 ; hsa-mir-4789-3p ; hsa-mir-3714 ; hsa-mir-568 ; hsa-mir-3908 ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-4766-3p ; hsa-mir-3924 ; hsa-mir-3175 ; hsa-mir-5196-5p ; hsa-mir-4763-3p ; hsa-mir-4747-5p ; hsa-mir-1207-5p ; hsa-mir-3202 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-5681a ; hsa-mir-9500 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-8064 ; hsa-mir-6854-5p ; hsa-mir-4643 ; hsa-mir-302f ; hsa-mir-3672 ; hsa-mir-4294 ; hsa-mir-6864-3p
Nearest miRNA
hsa-mir-10397/Upstream/615277; hsa-mir-103a-1/Downstream/961856;
Nearest TSS
ENST00000502646/Upstream/15316; ENST00000508791/Downstream/4551;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/82048, chr5-CpG: 78/Downstream/4664
Upstream sequence
actatgaagcatgacattccaagggtttagggattacttccaagaagccagcagtaaaggccagactgttctttggCAAGGTTAAATTTTTTACACCTGC
Downstream sequence
CCCTCTACATCGTAGAAGGGCCCGTTTCCTCAATTTTTTTGGATTATGTTATTTCTTCAATTCTCTCTTAGCTTTTCATCAGAGGTAAAAATAACGTTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate