Basic Information
VIS ID
TVIS44031924
Fusion event
HTLV-1-PCCA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q32.3
Reference genome
NCBI36/hg18
Start
99904958/100454703 (Hg38)
End
99904958/100454703 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13D
Target gene
PCCA
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-455-5p ; hsa-mir-7152-5p ; hsa-mir-568 ; hsa-mir-1273e ; hsa-mir-155-5p ; hsa-mir-4326 ; hsa-mir-15b-3p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-1297/Upstream/811554; hsa-mir-1267/Downstream/1512939;
Nearest TSS
ENST00000623511/Upstream/86204; ENST00000621936/Downstream/25582;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/365152, chr13-CpG: 51/Downstream/77439
Upstream sequence
TCCAGGTATAGATTTGTCTTTGTGAGAATCCTTGTAGAATTTTCTATATAAGTTTGTTTTTGTCAATATTGATAAACATGATCTTCAATGTTCAAAGGAG
Downstream sequence
AGTTCAATTTTAGACTAAGAGAAGTACTTCTGTTGTGTAAATAAGGTTCAAAAATAAGGTTACTGTTCAACTTAGAGAAAATACAAACTTAAAAATAATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate