Basic Information
VIS ID
TVIS44031939
Fusion event
HTLV-1-ATP11B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
NCBI36/hg18
Start
184001662/182801180 (Hg38)
End
184001662/182801180 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
ATP11B
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-652-3p ; hsa-mir-222-3p
Nearest miRNA
hsa-let-7g/Upstream/6286029; hsa-mir-1224/Downstream/1085620;
Nearest TSS
ENST00000440867/Upstream/7677; ENST00000482794/Downstream/32493;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/6686, chr3-CpG: 91/Downstream/178781
Upstream sequence
tgtgacccatcccaccaggccTTCCTTTGAAATTTTTAGCATGTAGTTTATCCTCCTTAACATTAAGTTATGGCTTATGCAGATAATCATACTTGTTTCT
Downstream sequence
CTTTAAAACTATTAGATTGTCCAAAATTTAGATGAAATACCAAATTAAGGATATTAATTAGTTAAGCTGTGTCTGTCTCCACATTTTAATTGGAAGTGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate