Basic Information
VIS ID
TVIS44031961
Fusion event
HTLV-1-PHF20 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
33943468/35892132 (Hg38)
End
33943468/35892132 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHF20
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-21-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6802-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-483-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/438035; hsa-mir-1-1/Downstream/2624431;
Nearest TSS
ENST00000382410/Upstream/22602; ENST00000420233/Downstream/25048;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/119804, chr20-CpG: 146/Downstream/61548
Upstream sequence
ctaattttttttgtttttttttgtttttttgttttttttaagcgggggacagtctcgttctttcgcccagtttcaagtacagtggcgtgatattggttca
Downstream sequence
ctgcaacctttgcctcccaggttcaagcgattctcctgcttcagcctcccgagtagatgggactacaggcatgcaccaccacgcctggctgatttttttt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate