Basic Information
VIS ID
TVIS44031978
Fusion event
HTLV-1-NLGN4X integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p22.32
Reference genome
NCBI36/hg18
Start
5946109/6018068 (Hg38)
End
5946109/6018068 (Hg38)
Orient
-
Location type
Intronic
Target gene
NLGN4X
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-26b-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-6507-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-5011-5p ; hsa-mir-6501-3p ; hsa-mir-4797-5p ; hsa-mir-6128 ; hsa-mir-1324 ; hsa-mir-6504-3p ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-323a-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-6831-3p ; hsa-mir-8066 ; hsa-mir-550b-3p ; hsa-mir-6758-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-5003-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-139-3p ; hsa-mir-942-5p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-1248 ; hsa-mir-1237-3p
Nearest miRNA
hsa-mir-3690-1/Upstream/3408814; hsa-let-7f-2/Downstream/365838;
Nearest TSS
ENST00000429181/Upstream/114715; ENST00000217961/Downstream/133398;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/114410, chrX-CpG: 138/Downstream/208011
Upstream sequence
ttacatttacaacgggtttattgggatataatcccactgtgaatcaaggaacatATTTtatatatgtatacatacacattagcatgtatacatatataga
Downstream sequence
cacatatatatacacacatatagaTCTGTGTGTGCATCACAAGGGCAAACAACTGatacatgtatatgtatacacacatatgtatgtatgtacacatata
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate