VISDB Viral Integration Site DataBase

VIS ID

TVIS44031982

Fusion event

HTLV-1-KREMEN1 integration

Validated

No

Detection method

HTS

Data source

Curated

Sample type

Disease

Not given

Quality evaluation

Normal

Reported year

2019

PubMed ID

Virus name

HTLV-1

Subtype

HTLV-1c

Reference genome

Chromosome

chr22

Cytoband

q12.1

Reference genome

Start

End

27834445/29108457 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-145-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-378a-3p ; hsa-mir-149-5p ; hsa-mir-30c-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-570-5p ; hsa-mir-3915 ; hsa-mir-3927-3p ; hsa-mir-548ag ; hsa-mir-4458 ; hsa-mir-4459 ; hsa-mir-548ai ; hsa-mir-4476 ; hsa-mir-4500 ; hsa-mir-4650-3p ; hsa-mir-4773 ; hsa-mir-6831-5p ; hsa-mir-6876-5p ; hsa-mir-548ba ; hsa-mir-431-5p ; hsa-mir-4435 ; hsa-mir-3928-3p ; hsa-mir-665 ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-30e-5p ; hsa-mir-6807-5p ; hsa-mir-4663 ; hsa-mir-4693-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-6761-5p ; hsa-mir-2681-3p ; hsa-mir-766-5p ; hsa-mir-4722-5p ; hsa-mir-6845-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-6165 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-302a-3p ; hsa-mir-373-3p ; hsa-mir-302b-3p ; hsa-mir-520a-3p ; hsa-mir-302e ; hsa-mir-372-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-520e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-4662a-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-483-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-1207-3p ; hsa-mir-646 ; hsa-mir-122-3p ; hsa-mir-129-5p ; hsa-mir-3149 ; hsa-mir-4775 ; hsa-mir-4735-5p ; hsa-mir-590-3p ; hsa-mir-188-3p ; hsa-mir-4707-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-532-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4438 ; hsa-mir-6762-3p ; hsa-mir-3140-3p ; hsa-mir-2467-3p ; hsa-mir-627-3p ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-5582-5p ; hsa-mir-3190-5p ; hsa-mir-3136-5p ; hsa-mir-331-3p ; hsa-mir-3622b-5p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-4439 ; hsa-mir-4513 ; hsa-mir-4732-3p ; hsa-mir-4757-5p ; hsa-mir-635 ; hsa-mir-6744-3p ; hsa-mir-6774-5p ; hsa-mir-6778-3p ; hsa-mir-6801-3p ; hsa-mir-6810-3p ; hsa-mir-6855-3p ; hsa-mir-6857-3p ; hsa-mir-6862-5p ; hsa-mir-6878-3p

Nearest miRNA

hsa-mir-1286/Upstream/648509; hsa-let-7a-3/Downstream/898592;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/34212, chr22-CpG: 81/Downstream/97101

Upstream sequence

GCTGGTGGAAAGAtggaaagaatgtggacatctgagtcacacccagttaggtttgaatcattatctgcttaatagctttaggcacaatgactctcagttg

Downstream sequence

tgcctgggtttcctcattggtgccttccagagttttttttgaagattaaatgaataaaatgcatgCTGCCCTAAGTCCTAGCACATATCAGGTAGACATG