Basic Information
VIS ID
TVIS44032035
Fusion event
HTLV-1-ME3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
NCBI36/hg18
Start
85851955/86463265 (Hg38)
End
85851955/86463265 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
ME3
miRNAs that regulate target gene
hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10392/Upstream/184867; hsa-let-7a-2/Downstream/1713237;
Nearest TSS
ENST00000527297/Upstream/31675; ENST00000526206/Downstream/34859;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/31711, chr11-CpG: 82/Downstream/208388
Upstream sequence
GTGCCTGTGTTTAGGAGGATGTATACACATGTGGCTGTCTGTGTGTCTGTACAGCTGGAGGCTGTGCACCAGGTGTGCCGCCTGCATGGACTTGTTTTCC
Downstream sequence
ACTTCCACCCTCTGGCCTTGGCAGCCCGGTGGGCTCAGGGGACTGGCTGTCCTGCTGCTGATTCATGGGTGAATTCATGCTGGGGAGCCGGTCAGGCTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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