Basic Information
VIS ID
TVIS44032038
Fusion event
HTLV-1-METTL25 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
NCBI36/hg18
Start
81368462/82450552 (Hg38)
End
81368462/82450552 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
METTL25
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-let-7c-5p
Nearest miRNA
hsa-let-7i/Upstream/1292091; hsa-mir-1178/Downstream/4294516;
Nearest TSS
ENST00000382841/Upstream/12037; ENST00000551645/Downstream/23947;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/91585, chr12-CpG: 79/Downstream/236331
Upstream sequence
tcatcatctttcacccagattattttaataatttcctagttggtctctctcttctacttttgctcactatagcctattctttacacaatagctagagtga
Downstream sequence
taccattgatatttttaagtgggctcctgctcacaatcttccagtggcttctgtttacctcagaagtaaagctaatgtttttcctgtgatctgcaaagcc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate