Basic Information
VIS ID
TVIS44032040
Fusion event
HTLV-1-ITGA9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p22.2
Reference genome
NCBI36/hg18
Start
37592858/37576363 (Hg38)
End
37592858/37576363 (Hg38)
Orient
-
Location type
Intronic
Target gene
ITGA9
miRNAs that regulate target gene
hsa-mir-194-5p ; hsa-mir-484 ; hsa-mir-452-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-452-3p ; hsa-mir-6794-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-759 ; hsa-mir-4639-3p ; hsa-mir-5000-5p ; hsa-mir-125b-1-3p
Nearest miRNA
hsa-mir-12127/Upstream/1831804; hsa-let-7g/Downstream/393041;
Nearest TSS
ENST00000440867/Upstream/124244; ENST00000461533/Downstream/107513;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/123316, chr3-CpG: 203/Downstream/284084
Upstream sequence
TGAATTTGGCCTTGGCTTGGAGCAGCCTTTTAACAGAAACACGCGTAACTTTCCTGCAGATGCACTTCCTGTGAATGAAGAGTCTTGATATATATTTTTC
Downstream sequence
TTTAACAAGAGAAAGCCAGGCTTTTGATTAATAATTTATATGTCAATGTTGGGATCTTCATTTTGTTATGAGAGATTTCAGTTACAACAGTGTGAGGTGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate