Basic Information
VIS ID
TVIS44032048
Fusion event
HTLV-1-MCF2L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
NCBI36/hg18
Start
112748311/113045996 (Hg38)
End
112748311/113045996 (Hg38)
Orient
+
Location type
Intronic
Target gene
MCF2L
Nearest miRNA
hsa-mir-1267/Upstream/2704967; hsa-mir-4502/Downstream/216924;
Nearest TSS
ENST00000623511/Upstream/1145; ENST00000464800/Downstream/18316;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/12482, chr13-CpG: 37/Downstream/1523
Nearest cancer related gene
MCF2L(OG, No orient, 0)
Upstream sequence
TTTCTCCTTTCCAAATCAGGCCATCTAGCTGCGACACTGAACTAGCCACCACCGCCTCCCTTCCCCAGTAACCCAGCCTCGCATGTAGCCACCCTCCTTT
Downstream sequence
CCAAGGACTTTCCCTTGGCATCCGAGAGTCTGTTTGCAGATTCTGCACGCTGCCTTCCATAGCAGAAGGGGAGCTGGGTTTGCTGTTGGTTTTAACCCAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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