Basic Information
VIS ID
TVIS44032059
Fusion event
HTLV-1-DCAF8L2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
27491886/27563848 (Hg38)
End
27491886/27563848 (Hg38)
Orient
-
Location type
Intronic
Target gene
DCAF8L2
Nearest miRNA
hsa-mir-23c/Upstream/7546661; hsa-let-7f-2/Downstream/931707;
Nearest TSS
ENST00000429181/Upstream/100507; ENST00000580017/Downstream/26534;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1005793, chrX-CpG: 28/Downstream/299989
Upstream sequence
GTAGTTTTCAAATATGCTTATGTAGAGGTGAATAATAATAGATCATTTTAATACACACTTATATATTGCTTACTAGGAAATGACTTTCTCATACAGTATG
Downstream sequence
TATTTGATTTTTTCGCAATAAGTAGACATTTCATTTGATTTGCTCTAATAGCTTCAATATTTAATAGCTTGTATATTTGTTAAGCTAAAAAAGGTCCAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate