Basic Information
VIS ID
TVIS44032061
Fusion event
HTLV-1-RYR3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
NCBI36/hg18
Start
31799117/33719624 (Hg38)
End
31799117/33719624 (Hg38)
Orient
-
Location type
Intronic
Target gene
RYR3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-367-5p
Nearest miRNA
hsa-mir-1268a/Upstream/2654483; hsa-mir-10393/Downstream/662445;
Nearest TSS
ENST00000557528/Upstream/73335; ENST00000636417/Downstream/4528;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/407822, chr15-CpG: 114/Downstream/318744
Upstream sequence
TTTTTTCCTCCatttttttatatttaaaatttCAACGTTTTAGCTTTATTATTCTTGTAGTGAGAAATTACAACTGAGAGGGCTGATGTATGTGCTACCT
Downstream sequence
GATAAGTACTGGAGGCCAAAACCATTCGAAAGTAGTGAACTGTGAGATACGTCCATGTCTGAGACCACTGGCTTTTAGAAATGTAGATTCTCCTGGGGCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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