Basic Information
VIS ID
TVIS44032082
Fusion event
HTLV-1-ZNF831 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
NCBI36/hg18
Start
57186182/59177732 (Hg38)
End
57186182/59177732 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF831
miRNAs that regulate target gene
hsa-mir-182-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4470 ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-6865-3p ; hsa-mir-34b-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/359419; hsa-mir-1-1/Downstream/1130742;
Nearest TSS
ENST00000382410/Upstream/54328; ENST00000371030/Downstream/13288;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/134565, chr20-CpG: 114/Downstream/13609
Upstream sequence
TCACCTGGCCCATCTCATTTAAAATTGCACTCTTCCCTCActggctggacgaggacggtctctcctgggattgcttggctcagctccacatggtcgctca
Downstream sequence
tcctcctgggagctcatctgggcttgttctcatggcagaagcagagcagaagcgtgcaagcttcttgggacctaggcacaccatccctaatgtgacacga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate