Basic Information
VIS ID
TVIS44032100
Fusion event
HTLV-1-ITGB2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
NCBI36/hg18
Start
45160500/44916157 (Hg38)
End
45160500/44916157 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITGB2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-146a-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-let-7c/Upstream/1306168; hsa-mir-6815/Downstream/562109;
Nearest TSS
ENST00000624081/Upstream/1874; ENST00000609694/Downstream/4698;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/12120, chr21-CpG: 134/Downstream/15256
Upstream sequence
gactataggtgcacaccactaggcccagctaatttttgtatttttagtagagatggagtttcaccatattggccaggctggtctcgaactcctgacctcg
Downstream sequence
tgatccgcctgcctcggcctcccaaagtgctgggattacaggcgtgagccactgcgcccggccTGATAGCACAAATTTTAAAGGCCACAATTTCTGGCCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate