Basic Information
VIS ID
TVIS44032125
Fusion event
HTLV-1-PHEX integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
NCBI36/hg18
Start
22065753/22137715 (Hg38)
End
22065753/22137715 (Hg38)
Orient
+
Location type
Intronic
Target gene
PHEX
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-4760-5p ; hsa-mir-8061 ; hsa-mir-4709-3p ; hsa-mir-4635 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-3935 ; hsa-mir-5011-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-5580-3p ; hsa-mir-4797-3p ; hsa-mir-545-5p ; hsa-mir-574-3p ; hsa-mir-8485 ; hsa-mir-4719 ; hsa-mir-186-5p ; hsa-mir-155-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-590-3p ; hsa-mir-3154 ; hsa-mir-802
Nearest miRNA
hsa-mir-23c/Upstream/2120528; hsa-let-7f-2/Downstream/6357840;
Nearest TSS
ENST00000429181/Upstream/47222; ENST00000323684/Downstream/35268;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/196132, chrX-CpG: 25/Downstream/1194452
Upstream sequence
gttctcaaggtgtggttccagaccagtagcagcagtggtccctgggaactcattagagatgcaaattttcacatccccacctgctgagctctgggagtag
Downstream sequence
ggctcagtgccttgtgttttacctggtgattctgctgcgtgaaaagggttgggaacccctgTCTTgtccttaccacttcacagcacacctgcctgacttc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate