Basic Information
VIS ID
TVIS44032131
Fusion event
HTLV-1-MYBL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
NCBI36/hg18
Start
41734384/43672330 (Hg38)
End
41734384/43672330 (Hg38)
Orient
-
Location type
Intronic
Target gene
MYBL2
miRNAs that regulate target gene
hsa-mir-30e-5p ; hsa-mir-149-3p ; hsa-mir-423-5p ; hsa-mir-505-3p ; hsa-mir-92a-3p ; hsa-mir-19b-3p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-1343-5p ; hsa-mir-138-5p ; hsa-mir-185-3p ; hsa-mir-298 ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3184-5p ; hsa-mir-3622a-3p ; hsa-mir-3622b-3p ; hsa-mir-4324 ; hsa-mir-4456 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4667-5p ; hsa-mir-4693-3p ; hsa-mir-4700-5p ; hsa-mir-4728-5p ; hsa-mir-4763-3p ; hsa-mir-5001-5p ; hsa-mir-5007-5p ; hsa-mir-6085 ; hsa-mir-637 ; hsa-mir-6761-5p ; hsa-mir-6763-5p ; hsa-mir-6779-5p ; hsa-mir-6785-5p ; hsa-mir-6813-5p ; hsa-mir-6825-5p ; hsa-mir-6858-5p ; hsa-mir-6883-5p ; hsa-mir-7106-3p ; hsa-mir-7155-5p ; hsa-mir-762 ; hsa-mir-8089 ; hsa-mir-939-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/2503252; hsa-mir-1-1/Downstream/735790;
Nearest TSS
ENST00000382410/Upstream/5173; ENST00000428529/Downstream/54367;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/4650, chr20-CpG: 209/Downstream/242127
Upstream sequence
GTACACTGATTTTTCTCTCCATTAATTATGCCTGTGTGTAGGCAAGGATTGAAAAGGGATTTGCAAAAATGGACATAAgccagacacggtggtgcacacc
Downstream sequence
tgtaatccaagttactttggaaggctgaggcaggaggatcccttgagcccaggagttcaagaccagtctgggtagcatactgagaccctgtcattacaaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate