Basic Information
VIS ID
TVIS44032135
Fusion event
HTLV-1-PROS1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q11.1
Reference genome
NCBI36/hg18
Start
95174701/93973167 (Hg38)
End
95174701/93973167 (Hg38)
Orient
+
Location type
Intronic
Target gene
PROS1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-494-3p
Nearest miRNA
hsa-let-7g/Upstream/6746890; hsa-mir-12124/Downstream/2386797;
Nearest TSS
ENST00000440867/Upstream/14413; ENST00000478400/Downstream/472;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/4858210, chr3-CpG: 39/Downstream/543
Upstream sequence
TGTTAAAAAATCCTCAGTACAAACGATCTGAGAAATAGAATACAGTATTTAACAGTCCTTTTGATTTCAGGGTTAGAAAGTGACATATATCTACTGCTAT
Downstream sequence
ACAAACCCTCAGTCATCCTAAAACATTTCGTTAATGTGAGACAAGCAAACCAAGCTCAAAGTCCAGAAATTGCAAAAGGGAGGCAGGTTTCAGGAGACGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate