Basic Information
VIS ID
TVIS44032179
Fusion event
HTLV-1-UQCRH integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
NCBI36/hg18
Start
46546432/46308173 (Hg38)
End
46546432/46308173 (Hg38)
Orient
+
Location type
Intronic
Target gene
UQCRH
miRNAs that regulate target gene
hsa-mir-4762-3p ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-3192-3p ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-7155-5p ; hsa-mir-4502 ; hsa-mir-1245b-3p ; hsa-mir-4778-5p ; hsa-mir-1272 ; hsa-mir-4463
Nearest miRNA
hsa-mir-12136/Upstream/1762621; hsa-mir-101-1/Downstream/4751664;
Nearest TSS
ENST00000473358/Upstream/4464; ENST00000460947/Downstream/1748;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4809, chr1-CpG: 47/Downstream/32494
Upstream sequence
AAGAGATATGAAGGTGCTTTATAAACTGGAGAGTATTAAGCACACTTAGGTTCTTGTTAATGAAAGTGAGATGGTGTCTCtgtcttgaaatatacctggg
Downstream sequence
attcgttttaaccaagtatggtaaggtgacagacctggagacaaccgcctttgaaagaagagtttattattacttaaatttcctgaaagagagggatatg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate