Basic Information
VIS ID
TVIS44032180
Fusion event
HTLV-1-PTAFR integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
NCBI36/hg18
Start
28370594/28171496 (Hg38)
End
28370594/28171496 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTAFR
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6788-3p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-4716-5p ; hsa-mir-4494 ; hsa-mir-4463 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-2276-3p ; hsa-mir-1281 ; hsa-mir-4485-5p ; hsa-mir-186-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-6749-3p ; hsa-mir-3156-3p ; hsa-mir-188-3p ; hsa-mir-3157-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6778-3p ; hsa-mir-149-5p ; hsa-mir-532-3p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4301 ; hsa-mir-660-3p ; hsa-mir-125b-2-3p ; hsa-mir-5697 ; hsa-mir-562 ; hsa-mir-1307-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-12136/Upstream/1616903; hsa-mir-101-1/Downstream/2567660;
Nearest TSS
ENST00000473358/Upstream/82800; ENST00000465645/Downstream/5692;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/82695, chr1-CpG: 36/Downstream/61138
Upstream sequence
atagaaggtactcaatacatgagttactTCCTGTTCTGACATGCCCTGTTGCTTGATATTTGTGCCCTGACCTGGCCGTGCCGACCACACCCTCTAATGT
Downstream sequence
TACCTCTCACAGAGTGGTTTCAATACCATTTCTCCAAGATGCAGAAGGATTTGAGCGACGAATTAAGGGAGGAGAAATCCTGACCTCTGGGGAATTCTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate