Basic Information
VIS ID
TVIS44032182
Fusion event
HTLV-1-DNAH9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
NCBI36/hg18
Start
11472434/11628392 (Hg38)
End
11472434/11628392 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
DNAH9
miRNAs that regulate target gene
hsa-mir-665 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-5582-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4451 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4468 ; hsa-mir-6840-3p ; hsa-mir-4459 ; hsa-mir-4756-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-129-5p ; hsa-mir-4524a-3p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-4797-5p ; hsa-mir-5007-5p ; hsa-mir-7855-5p
Nearest miRNA
hsa-mir-1253/Upstream/3441388; hsa-mir-10226/Downstream/453507;
Nearest TSS
ENST00000595228/Upstream/10992; ENST00000583192/Downstream/75808;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/29381, chr17-CpG: 67/Downstream/368733
Upstream sequence
ACTCAGGAGGGGATCCTCCCCAAGGCTTCTGGGTTGCGCCGTCCACCTGTCATTGGATCTCAAGCACACCTGGGACACTGCCACATTAATAACAGCGATG
Downstream sequence
Atactgtgtgtgcaggcctggcctaaatcccaggcttgagttaactgacttagcactcagcatcatgctacaaggtgttattattattctgcagcagatg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate