Basic Information
VIS ID
TVIS44032193
Fusion event
HTLV-1-MRPS14 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
NCBI36/hg18
Start
173251639/175015880 (Hg38)
End
173251639/175015880 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1G
Target gene
MRPS14
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-181a-5p ; hsa-mir-16-5p ; hsa-mir-606 ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-455-3p ; hsa-mir-1227-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4252 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-5186 ; hsa-mir-1247-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-5089-3p ; hsa-mir-4795-3p ; hsa-mir-513a-5p ; hsa-mir-3146 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-543 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-5705 ; hsa-mir-4522 ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-4682 ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-1306-5p ; hsa-mir-6818-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-4724-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2871236; hsa-mir-1182/Downstream/952490;
Nearest TSS
ENST00000473358/Upstream/1056; ENST00000622870/Downstream/7535;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15392, chr1-CpG: 32/Downstream/7349
Upstream sequence
CTAGACTGCGGTGCAAGCAAAATAACACATTAAAATAACACAAATTAAATGAAAGTATATAAAAGCCAAAAATTAACAAAAGCTTATGCATGTGTTACCA
Downstream sequence
TTATGAACTAACAGAATTACATAAAACAACATGATTgccaggcacagtggctcacgcctataatcccagcactttgggacgccgaggcaggcggatcatc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate