Basic Information
VIS ID
TVIS44032195
Fusion event
HTLV-1-SDHC integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
NCBI36/hg18
Start
159579546/161343132 (Hg38)
End
159579546/161343132 (Hg38)
Orient
-
Location type
Intronic
Target gene
SDHC
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-9-3p ; hsa-mir-8084
Nearest miRNA
hsa-mir-101-1/Upstream/115871; hsa-mir-1182/Downstream/813975;
Nearest TSS
ENST00000473358/Upstream/19518; ENST00000437833/Downstream/24742;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/28471, chr1-CpG: 77/Downstream/46577
Upstream sequence
GAGCAGATGGCAACCTTCAGGTCCTATCGTGTAAGTGTGCTCTTGCTCCAGAAATTTGATGCCAAATAGAGCTTTCGAGGTAGGAAAGGGAGTTTCTATT
Downstream sequence
GACTTTTGCTTTGTTGAAGCAGTGGTGGTATTGGAAAAGTGCTCTTGTTTCTGTCTTCTGAGACCCTGAAGGATCTCTCCTAGGCTTCTGTAGACTATGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate