Basic Information
VIS ID
TVIS44032210
Fusion event
HTLV-1-IL1RN integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
NCBI36/hg18
Start
113594488/113120440 (Hg38)
End
113594488/113120440 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
IL1RN
miRNAs that regulate target gene
hsa-mir-125a-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/1349306; hsa-mir-10b/Downstream/462519;
Nearest TSS
ENST00000437798/Upstream/2459; ENST00000472292/Downstream/7121;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/69261, chr2-CpG: 80/Downstream/36664
Upstream sequence
tatgtatgtatgtatgtatgtatgtatgcatgtatctatctatCTGTTGTCTAATAAAATGGATCACATCTCTGCTAATAAAAACACTACACTGGCAGGG
Downstream sequence
TACAATTATAATCATTAACTGTGCCTGGAATTTGCAGCAGCAGCCACCAGAGGTACCAGTGCCCTTTAAGGGTTCATAATTtagaataatccaattatct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate