Basic Information
VIS ID
TVIS44032216
Fusion event
HTLV-1-STT3B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p23
Reference genome
NCBI36/hg18
Start
31550563/31534067 (Hg38)
End
31550563/31534067 (Hg38)
Orient
-
Location type
Intronic
Target gene
STT3B
miRNAs that regulate target gene
hsa-mir-15b-5p ; hsa-mir-23a-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-12127/Upstream/372280; hsa-let-7g/Downstream/972216;
Nearest TSS
ENST00000440867/Upstream/442; ENST00000436236/Downstream/62739;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/277, chr3-CpG: 104/Downstream/446410
Upstream sequence
TGAAAGCTAGCTACTCTTATTTATTTATCATTAGGTATTTTAAAGAGTGGCTTTTTTTCAGAGCTCTTAAGTGCACTCAGCACCTTACTGTTTCACTATC
Downstream sequence
GTCTTGGGTTGCTTTTTAGAACAAGATCCTTACCCTGTTAGCCACTGTCACCCTTAGTGTGTTATGCACAGTATCTGAAAGCATTGCATTAGTTCCTTTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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