Basic Information
VIS ID
TVIS44032225
Fusion event
HTLV-1-BTBD9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
NCBI36/hg18
Start
38493402/38417648 (Hg38)
End
38493402/38417648 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
BTBD9
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-30e-5p ; hsa-mir-149-5p ; hsa-mir-26a-5p ; hsa-let-7b-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-5692a ; hsa-mir-574-5p ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-4719 ; hsa-mir-1178-3p ; hsa-mir-369-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6781-5p ; hsa-mir-4268 ; hsa-mir-4660 ; hsa-mir-766-3p ; hsa-mir-7112-5p ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-3918 ; hsa-mir-6736-3p ; hsa-mir-3065-3p ; hsa-mir-6871-3p ; hsa-mir-6749-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-600 ; hsa-mir-2116-3p ; hsa-mir-5193 ; hsa-mir-4700-3p ; hsa-mir-374c-5p ; hsa-mir-4643 ; hsa-mir-466 ; hsa-mir-4789-3p ; hsa-mir-655-3p
Nearest miRNA
hsa-mir-1236/Upstream/862226; hsa-mir-10398/Downstream/656666;
Nearest TSS
ENST00000381078/Upstream/274651; ENST00000412822/Downstream/64044;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/597874, chr6-CpG: 77/Downstream/221781
Upstream sequence
ggatcacttgagtctgcgactttgatactagcctgggcagcatagcaaaaccacgtctctacaaaaaatacaaaaataagctgggcatggtggcacgtgc
Downstream sequence
ctatagtcccagctacttgggggctgaggtgggaggatcactggagcctgggaggttgaggctgcagtgagccctgattgcgccactgcattccagccta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate