Basic Information
VIS ID
TVIS44032232
Fusion event
HTLV-1-SNRPC integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
NCBI36/hg18
Start
34848883/34773128 (Hg38)
End
34848883/34773128 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
SNRPC
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-296-3p ; hsa-let-7f-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-1236/Upstream/532392; hsa-mir-10398/Downstream/697380;
Nearest TSS
ENST00000381078/Upstream/15216; ENST00000192788/Downstream/18887;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/15599, chr6-CpG: 99/Downstream/18629
Upstream sequence
GTGTACATTCATGAAATAGCTCCTGGTTATATGGTGGATAACACTGATTAAAAGAGCTGACTGAAAAACATGTGACTTAGTTGTGAATTTCCCTGAGTGA
Downstream sequence
GAAAAAAAGGTCAGTTTAGGGAACTAGTGTCCCTGGCGATTTCTGGAAAGCAGTCTATTAATAGTTTCCCCCTTACTATCATTAGATCATGATTCCCATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate