Basic Information
VIS ID
TVIS44032245
Fusion event
HTLV-1-ARHGAP10 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.23
Reference genome
NCBI36/hg18
Start
148910159/147769558 (Hg38)
End
148910159/147769558 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGAP10
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-214-3p
Nearest miRNA
hsa-mir-12113/Upstream/424841; hsa-mir-1305/Downstream/13037;
Nearest TSS
ENST00000502981/Upstream/37495; ENST00000513548/Downstream/91425;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/36791, chr4-CpG: 294/Downstream/672502
Upstream sequence
ATCAAGGATTTTATTTCAGGTATGTGCTGCATTGCTTCTCTTTATGTAATAAATTCCTTGTTAACTGACATTGTTTCCCGGGGATTTCCGTATGTTAACA
Downstream sequence
AGTTCTTTCTACAGAGATGATTAATACTTACGGTGATCACCCTGAGGTTCCACAAAACCCTCTTGAATCATCAGAGATGACATTCTACTCATTGTAACTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate