Basic Information
VIS ID
TVIS44032257
Fusion event
HTLV-1-WASHC5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
NCBI36/hg18
Start
126136588/125055164 (Hg38)
End
126136588/125055164 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
WASHC5
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-324-5p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-12123/Upstream/233106; hsa-mir-10400/Downstream/2740798;
Nearest TSS
ENST00000518652/Upstream/6133; ENST00000518013/Downstream/28692;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/56212, chr8-CpG: 39/Downstream/36354
Upstream sequence
TTCCCACTACCTTCAAGTACTAAGAGAAATAAAGATTACAATGCTTTCTCTTCCTCCATCAATAAGTGAGTAAAACGggctgggcaccgtggctcatgcc
Downstream sequence
tataatcccagcactttgaaaggccacgacagatggatcacttgaggtcaggagtttgagaccagcctggccaacatggtgaaactcgtctctattaaaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate