Basic Information
VIS ID
TVIS44032258
Fusion event
HTLV-1-JPH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
NCBI36/hg18
Start
75387681/74312891 (Hg38)
End
75387681/74312891 (Hg38)
Orient
-
Location type
Intronic
Target gene
JPH1
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-21-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-4751 ; hsa-mir-186-3p ; hsa-mir-6847-5p ; hsa-mir-330-3p ; hsa-mir-449b-3p ; hsa-mir-6835-3p
Nearest miRNA
hsa-mir-124-1/Upstream/9933634; hsa-mir-10400/Downstream/235652;
Nearest TSS
ENST00000518652/Upstream/68103; ENST00000523640/Downstream/8239;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/336201, chr8-CpG: 52/Downstream/2215
Upstream sequence
ttgtttttctgtgactgacttctttcatttgcataatgAATTAAGCATTTTAAACATAGCTAAGTAACTATGAAGTAACTAACTGGCTAAAAGTATAAGG
Downstream sequence
TCTTAAACTAAAGATCTCTTGATTATAACTATATAATACAGTATTCCCAAATGAAATAATACTACCCCCAAAAGACTTGCAACAGAGAGAACATGGCTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate