Basic Information
VIS ID
TVIS44032266
Fusion event
HTLV-1-LRCH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
NCBI36/hg18
Start
46210639/46738503 (Hg38)
End
46210639/46738503 (Hg38)
Orient
-
Location type
Intronic
Target gene
LRCH1
miRNAs that regulate target gene
hsa-mir-587 ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-6884-3p ; hsa-mir-654-3p ; hsa-mir-5583-3p ; hsa-mir-4517
Nearest miRNA
hsa-mir-2276/Upstream/2542303; hsa-mir-1267/Downstream/3257912;
Nearest TSS
ENST00000623511/Upstream/58469; ENST00000452352/Downstream/43065;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/183932, chr13-CpG: 67/Downstream/58125
Upstream sequence
ATATTCGCATTTTTTGTGTTAAAGGTTTTATATATGAAAGTCATAATAGCGTTCCCACTTTACACCTCTTGTGAGGGTTTAGGAAATTACACATACCACT
Downstream sequence
GATTGAAGTTTTTGTTTTTGAAAGACAATCTATAAATTGAAGCTACTGTTTTTTTGTTTTAATCTTAAGAATAAGAGAAATGGGTCCCTTATCTTCTCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate